Tailor-made Antibodies
and Tools for Life Science

Synaptophysin1 antibody - 101 011C2 K.O.

Synaptophysin is a major synaptic vesicle membrane protein and a useful neuroendocrine tumor marker
Mouse monoclonal purified IgG
Cat. No.: 101 011C2
Amount: 50 µg
Price: $480.00
Cat. No. 101 011C2 50 µg purified IgG, lyophilized, fluorescence-labeled with Cyanine 2.
Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Either add 1:1 (v/v) glycerol, then aliquot and store at -20°C until use, or store aliquots at -80°C without additives.
Reconstitute immediately upon receipt! Avoid bright light when working with the antibody to minimize photo bleeching of the fluorescent dye.
Applications
 
WB: N/A
IP: N/A
ICC: 1 : 100 up to 1 : 1000 gallery  
IHC: not tested yet
IHC-P: not tested yet
Label Cyanine 2
Clone 7.2
Subtype IgG1 (λ light chain)
Immunogen Full-length recombinant rat synaptophysin (UniProt Id: P07825)
Epitop AA 219 to 307 from rat Synaptophysin1 (UniProt Id: P07825)
Reactivity Reacts with: human (P08247), rat (P07825), mouse (Q62277), mammals.
Weaker signal: zebrafish, other vertebrates.
Other species not tested yet.
Specificity K.O. validated
Remarks

Widely used as marker for nerve terminals and neuroendocrine tumors. For unknown reason, neuronal synaptophysin is better recognised than neuroendocrine synaptophysin. If this is a problem, the polyclonal rabbit antibody, cat. no. 101 002 or 101 203 are recommended.

Data sheet 101_011c2.pdf

References for Synaptophysin1 - 101 011C2

Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function.
Parra-Rivas LA, Madhivanan K, Aulston BD, Wang L, Prakashchand DD, Boyer NP, Saia-Cereda VM, Branes-Guerrero K, Pizzo DP, Bagchi P, Sundar VS, et al.
Neuron (2023) 11124: 4006-4023.e10. 101 011C2 WB; tested species: mouse
Cat. No.: 101 011C2
Amount: 50 µg
Price: $480.00